The Effectiveness of Inhaled Rosemary essential Oil in Improving Hemoglobin Concentration and Reducing Anemia Symptoms Among Pregnant Women
Abstract
Background: Anemia during pregnancy is a global health concern that affects both maternal and fetal well-being. Iron supplementation is the primary treatment. However, its effectiveness is often hindered by poor adherence due to gastrointestinal side effects. Rosemary (Rosmarinus officinalis L.) essential oil has demonstrated antioxidant and hematopoietic potential, suggesting its utility as a complementary therapy. This study aims to evaluate the effectiveness of inhaled rosemary essential oil in improving hemoglobin concentration and reducing anemia releated symptoms among second trimester pregnant women with mild to moderate anemia. Methods: A quasi-experimental pretest-posttest control group design was utilized with 60 pregnant women who were randomly assigned to intervention (n=30) and control (n=30) groups. The intervention group inhaled rosemary essential oil for 15 minutes twice day throughout a duration of four weeks, while both groups continued iron supplementation. Hemoglobin levels were measured pre and post intervention using a hematology analyser, and anemia symptoms (fatigue, dizziness and shortness of breath) were assessed using the Visual Analog Scale (VAS). Results: The intervention group showed a significantly greater increase in hemoglobin levels compared to the control group (+1,20 g/dL vs. +0,40 g/dL; p<0,001), indicating improvement in clinical symptoms of anemia. Conclusions: Inhalation of rosemary essential oil signicantly improves hemoglobin concentration and alleviates anemia related symptoms in pregnant women. It offers a safe, natural and non-invasive complementary approach to enhance maternal health during pregnancy.
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Gadhiraju S, Sujatha T, Putcha UK, Surekha MV. Effects of Maternal Iron Deficiency Anemia on Placenta and Cord Blood Iron Status with Specific Reference to the Iron Transport Protein Ferroportin 1. Journal of the Anatomical Society of India. 2022;71(1):34–41. http://dx.doi.org/10.4103/jasi.jasi_158_20
Gomaa AH, Mohamed M, Radwan M, El Sheikh A. Severity of Maternal Iron Deficiency Anemia and Risk for Low Birth Weight Babies. Al-Azhar International Medical Journal. 2021;2(1):5. http://dx.doi.org/10.21608/aimj.2021.57248.1405
Rahman MA, Khan MN, Rahman MM. Maternal anaemia and risk of adverse obstetric and neonatal outcomes in South Asian countries: A systematic review and meta-analysis. Public Health in Practice. 2020;1:100021. http://dx.doi.org/10.1016/j.puhip.2020.100021
Benson CS, Shah A, Frise MC, Frise CJ. Iron deficiency anaemia in pregnancy: A contemporary review. Obstetric Medicine. 2020;14(2):67–76. http://dx.doi.org/10.1177/1753495x20932426
James AH. Iron Deficiency Anemia in Pregnancy. Obstetrics & Gynecology. 2021;138(4):663–674. http://dx.doi.org/10.1097/aog.0000000000004559
Balarajan Y, Ramakrishnan U, Özaltin E, Shankar AH, Subramanian S. Anaemia in low-income and middle-income countries. The Lancet. 2011;378(9809):2123–2135. http://dx.doi.org/10.1016/s0140-6736(10)62304-5
De Oliveira JR, Camargo SEA, De Oliveira LD. Rosmarinus officinalis L. (rosemary) as therapeutic and prophylactic agent. Journal of Biomedical Science. 2019;26(5):1-22. https://doi.org/10.1186/s12929-019-0499-8
Ghasemzadeh Rahbardar M, Hosseinzadeh H. Toxicity and safety of rosemary (Rosmarinus officinalis): a comprehensive review. Naunyn-Schmiedeberg’s Archives of Pharmacology. 2024;398(1):9–23. http://dx.doi.org/10.1007/s00210-024-03336-9
Ciliberti MG, Albenzio M, Sevi A, Frabboni L, Marino R, Caroprese M. Immunomodulatory Role of Rosmarinus officinalis L., Mentha x piperita L., and Lavandula angustifolia L. Essential Oils in Sheep Peripheral Blood Mononuclear Cells. Veterinary Sciences. 2024;11(4):157. http://dx.doi.org/10.3390/vetsci11040157
El-Demerdash FM, El-Sayed RA, Abdel-Daim MM. Hepatoprotective potential of Rosmarinus officinalis essential oil against hexavalent chromium-induced hematotoxicity, biochemical, histological, and immunohistochemical changes in male rats. Environmental Science and Pollution Research. 2021;28(14):17445–17456. http://dx.doi.org/10.1007/s11356-020-12126-8
Filiptsova OV, Gazzavi-Rogozina LV, Timoshyna IA, Naboka OI, Dyomina YeV, Ochkur AV. The essential oil of rosemary and its effect on the human image and numerical short-term memory. Egyptian Journal of Basic and Applied Sciences. 2017;4(2):107–111. http://dx.doi.org/10.1016/j.ejbas.2017.04.002
Chelemal Dezfoulnejad M, Molayemraftar T. Use of dietary rosemary (Rosmarinus officinalis L.) extract as a growth promotor and immunostimulant in common carp. Aquaculture Research. 2021;53(4):1553–1562. http://dx.doi.org/10.1111/are.15690
Agarwal AM, Rets A. Laboratory approach to investigation of anemia in pregnancy. International Journal of Laboratory Hematology. 2021;43(S1):65–70. http://dx.doi.org/10.1111/ijlh.13551
Naimi M, Vlavcheski F, Shamshoum H, Tsiani E. Rosemary Extract as a Potential Anti-Hyperglycemic Agent: Current Evidence and Future Perspectives. Nutrients. 2017;9(9):968. http://dx.doi.org/10.3390/nu9090968
Santos Rodrigues AP, Faria e Souza BS, Alves Barros AS, de Oliveira Carvalho H, Lobato Duarte J, Letícia Elizandra Boettger M, et al. The effects of Rosmarinus officinalis L. essential oil and its nanoemulsion on dyslipidemic Wistar rats. Journal of Applied Biomedicine. 2020;18(4):126–135. http://dx.doi.org/10.32725/jab.2020.016
Hashemi SMB, Gholamhosseinpour A, Barba FJ. Rosmarinus officinalis L. Essential Oils Impact on the Microbiological and Oxidative Stability of Sarshir (Kaymak). Molecules. 2023;28(10):4206. http://dx.doi.org/10.3390/molecules28104206
Elachouri M, Ouasti I, Fakchich J, Bussmann RW. Rosmarinus officinalis L. Lamiaceae. In: Ethnobotany of Northern Africa and Levant. New York: Springer; 2024.
El-Demerdash FM, El-Sayed RA, Abdel-Daim MM. Hepatoprotective potential of Rosmarinus officinalis essential oil against hexavalent chromium-induced hematotoxicity, biochemical, histological, and immunohistochemical changes in male rats. Environmental Science and Pollution Research. 2021;28(14):17445–17456. http://dx.doi.org/10.1007/s11356-020-12126-8
El-Gindy YM, Zahran SM, Ahmed MAR, Salem AZM, Misbah TR. Influence of dietary supplementation of clove and rosemary essential oils or their combination on growth performance, immunity status, and blood antioxidant of growing rabbits. Tropical Animal Health and Production. 2021;53(5):482. http://dx.doi.org/10.1007/s11250-021-02906-w
Khodabandeh Shahraki F, Nabiuni M, Farhadi M, Amini E. The Effect of Hydroalcoholic Rosmarinus Officinalis (Rosemary) on Memory Retention Deficit in Young Offspring Rat Induced by Maternal Sleep Deprivation. Pharmaceutical and Biomedical Research. 2020;6(2):157-168. http://dx.doi.org/10.18502/pbr.v6i2.3808
Abo Ghanima MM, Elsadek MF, Taha AE, Abd El-Hack ME, Alagawany M, Ahmed BM, et al. Effect of Housing System and Rosemary and Cinnamon Essential Oils on Layers Performance, Egg Quality, Haematological Traits, Blood Chemistry, Immunity, and Antioxidant. Animals. 2020;10(2):245. http://dx.doi.org/10.3390/ani10020245
DOI: https://doi.org/10.33846/hd20605
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